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BPC-157 meets this criterion because its clinical development (PL 14736, Diagen) stalled at phase II in 2014 and never obtained registration as a drug

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While the ATTAIN-1 trial successfully met its predetermined weight loss endpoints versus placebo, the weight loss percentage realized in the highest dose fell modestly short of investor expectations, with average weight loss of 12.4% versus placebo at 0.9%

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